2D 3D Download Zoom

Vandetanib-d4
Catalog No.	V097102	Name	Toronto Research Chemicals
CAS Number		Website	http://www.trc-canada.com
M. F.	C22H24BrFN4O2	Telephone	+1 (416) 665-9696
M. W.	475.3539632	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage		Chembase ID: 179440

PRICE

Please log in

SYNONYMS

IUPAC name

N-(4-bromo-2-fluorophenyl)-6-methoxy-7-{[1-methyl(2,2,6,6-²H₄)piperidin-4-yl]methoxy}quinazolin-4-amine

IUPAC Traditional name

N-(4-bromo-2-fluorophenyl)-6-methoxy-7-{[1-methyl(2,2,6,6-²H₄)piperidin-4-yl]methoxy}quinazolin-4-amine

Synonyms

4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[[1-methyl(piperidin-4-yl)-d4]methoxy]quinazoline

Zactima-d4

N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[[1-methyl-4-(piperidinyl-d4)]methoxy]-4-quinazolinamine

ZD 6474-d4

DATABASE IDS

PROPERTIES

MSDS Link	Download
Certificate of Analysis	Download

DETAILS

Description (English)

A labelled Vandetanib; a once-daily oral inhibitor of vascular endothelial growth factor receptor-2 and epidermal growth factor receptor kinase activity. The activity of vandetanib plus docetaxel was assessed in patients with previously treated non-small-

REFERENCES

Bruns, C., et al.: Clin. Cancer Res., 6, 1936 (2000)
Hennequin, L., et al.: J. Med. Chem., 45, 1300 (2000)
Park, M., et al.: J. Biol. Chem., 278, 50624 (2000)
Arao, T., et al.: Cancer Res., 64, 9101 (2000)
Prueitt, R., et al.: Int. J. Cancer, 120, 796