Vancomycin Hydrochloride

• Catalog No.: V096500
• CAS Number: 1404-93-9
• M. F.: C66H76Cl3N9O24
• M. W.: 1485.71454
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1S,2R,18R,22S,25R,28R,40S)-48-{[(2S,3R,4S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-22-(carbamoylmethyl)-47,49-dichloro-2,18,32,35,37-pentahydroxy-19-[(2R)-4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2^3,^6.2^1^4,^1^7.1^8,^1^2.1^2^9,^3^3.0^1^0,^2^5.0^3^4,^3^9]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34(39),35,37,46,49-pentadecaene-40-carboxylic acid hydrochloride
• IUPAC Traditional name: (1S,2R,18R,22S,25R,28R,40S)-48-{[(2S,3R,4S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-22-(carbamoylmethyl)-47,49-dichloro-2,18,32,35,37-pentahydroxy-19-[(2R)-4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2^3,^6.2^1^4,^1^7.1^8,^1^2.1^2^9,^3^3.0^1^0,^2^5.0^3^4,^3^9]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34(39),35,37,46,49-pentadecaene-40-carboxylic acid hydrochloride
• Synonyms: Lyphocin; Vancocin Hydrochloride; Vancor; Meek; Vancocine Hydrochloride; Vancocyn

DATABASE IDS

• CAS Number: 1404-93-9

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: >190°C (dec.)
• Solubility: Methanol
• Solubility: Water
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Amphoteric glycopeptide antibiotic produced by Streptomyces orientalis discovered in soil. Inhibits bacterial cell wall synthesis by binding to peptidoglycan. Antibacterial.

REFERENCES

• Marshall, F.J., et al.: J. Med. Chem., 8, 18 (1965)
• Cunha, B.A., et al.: Med. Clin. North Am., 79, 817 (1965)
• Li, L., et al.: Ther. Drug Monit., 17, 366 (1965)