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Vancomycin Hydrochloride

Catalog No. V096500 Name Toronto Research Chemicals
CAS Number 1404-93-9 Website http://www.trc-canada.com
M. F. C66H76Cl3N9O24 Telephone +1 (416) 665-9696
M. W. 1485.71454 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 179437

SYNONYMS

IUPAC name
(1S,2R,18R,22S,25R,28R,40S)-48-{[(2S,3R,4S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-22-(carbamoylmethyl)-47,49-dichloro-2,18,32,35,37-pentahydroxy-19-[(2R)-4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34(39),35,37,46,49-pentadecaene-40-carboxylic acid hydrochloride
IUPAC Traditional name
(1S,2R,18R,22S,25R,28R,40S)-48-{[(2S,3R,4S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-22-(carbamoylmethyl)-47,49-dichloro-2,18,32,35,37-pentahydroxy-19-[(2R)-4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34(39),35,37,46,49-pentadecaene-40-carboxylic acid hydrochloride
Synonyms
Lyphocin
Vancocin Hydrochloride
Vancor
Meek
Vancocine Hydrochloride
Vancocyn

DATABASE IDS

CAS Number 1404-93-9

PROPERTIES

Certificate of Analysis Download
Apperance White to Off-White Solid
Melting Point >190°C (dec.)
Solubility Methanol
Solubility Water
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
Amphoteric glycopeptide antibiotic produced by Streptomyces orientalis discovered in soil. Inhibits bacterial cell wall synthesis by binding to peptidoglycan. Antibacterial.

REFERENCES

  • Marshall, F.J., et al.: J. Med. Chem., 8, 18 (1965)
  • Cunha, B.A., et al.: Med. Clin. North Am., 79, 817 (1965)
  • Li, L., et al.: Ther. Drug Monit., 17, 366 (1965)