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UBP 301_Molecular_structure_CAS_569371-10-4)
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UBP 301

Catalog No. U103500 Name Toronto Research Chemicals
CAS Number 569371-10-4 Website http://www.trc-canada.com
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SYNONYMS

IUPAC name
3-{1-methyl-7-oxo-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-5-yl}-N-[2-(1-methylpyrrolidin-2-yl)ethyl]-4-propoxybenzene-1-sulfonamide
IUPAC Traditional name
udenafil
Synonyms
(αS)-α-Amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-5-iodo-2,4-dioxo-1(2H)-pyrimidinepropanoic acid

DATABASE IDS

CAS Number 569371-10-4

PROPERTIES

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DETAILS

Description (English)
UBP 301 is an antagonist of kainate receptors. UBP 301 is the N3-4-carboxybenzyl substituted analog II of Willardiine, which was found to be equipotent at AMPA and GLUK5-containing kainate receptors in the neonatal rat spinal cord.

REFERENCES

  • Fletcher, E., et al.: Pharmacol. Ther., 70, 65 (1996)
  • Bleakman, D., et al.: Neuropharmacology, 37, 1187 (1996)
  • Chittajallu, R., et al.: Trends Pharmacol. Sci., 20, 26 (1996)
  • Valgeirsson, J., et al.: J. Med. Chem., 47, 6948 (1996)