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Tyrphostin 25

Catalog No. T925000 Name Toronto Research Chemicals
CAS Number 118409-58-8 Website http://www.trc-canada.com
M. F. C10H6N2O3 Telephone +1 (416) 665-9696
M. W. 202.16624 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Chembase ID: 105108

SYNONYMS

IUPAC name
2-[(3,4,5-trihydroxyphenyl)methylidene]propanedinitrile
IUPAC Traditional name
2-[(3,4,5-trihydroxyphenyl)methylidene]propanedinitrile
Synonyms
([3,4,5-Trihydroxybenzylidene]malononitrile)

DATABASE IDS

CAS Number 118409-58-8

PROPERTIES

Certificate of Analysis Download
Apperance Yellow Green Powder
Melting Point ~220°C dec.
Solubility Acetone
Solubility Chloroform
Solubility Dichloromethane
Solubility DMF
Solubility DMSO
Solubility Methanol
MSDS Link Download
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DETAILS

Description (English)
An inhibitor of epidermal growth factor receptor tyrosine kinase activity and has a reported IC50 of 15 μM for the autophosphorylation of the EGF-receptor.

REFERENCES

  • Gazit, A., et al.: J. Med. Chem., 32, 2344 (1989)