(+)-(S)-Tylophorine-d8

• Catalog No.: T898202
• M. F.: C24H27NO4
• M. W.: 393.47548

SYNONYMS

• IUPAC name: (20S)-5,6,9,10-tetramethoxy(15,15,17,17,18,18,21,21-^2H₈)-16-azapentacyclo[12.7.0.0^2,^7.0^8,^1^3.0^1^6,^2^0]henicosa-1(14),2,4,6,8,10,12-heptaene
• IUPAC Traditional name: (20S)-5,6,9,10-tetramethoxy(15,15,17,17,18,18,21,21-^2H₈)-16-azapentacyclo[12.7.0.0^2,^7.0^8,^1^3.0^1^6,^2^0]henicosa-1(14),2,4,6,8,10,12-heptaene
• Synonyms: (S)-9,11,12,13,13a,14-Hexahydro-2,3,6,7-tetramethoxydibenzo[f,h]pyrrolo[1,2-b]isoquinoline-d8; NSTP 0G01-d8; (13aS)-9,11,12,13,13a,14-Hexahydro-2,3,6,7-tetramethoxydibenzo[f,h]pyrrolo[1,2-b]isoquinoline-d8; NSC 76387-d8; Tylophorin-d8; NSC 717335-d8; Tylophorine-d8; (+)-Tylophorine-d8

DETAILS

Description (English)

Labelled (+)-(S)-Tylophorine. (+)-(S)-Tylophorine is a a major alkaloid of Tylophora indica. (+)-(S)-Tylophorine is an immunosuppressant and inflammation inhibitor. (+)-(S)-Tylophorine showed antiproliferative activity and induction of apoptosis in tumor

REFERENCES

• Gopalakrishnan, C. et a.: Ind. J. Med. Chem., 71, 940 (1980)
• Ganguly, T.et al.: Phytomedicine, 9, 288 (1980)
• Gao, W. et al.: Cancer, Res., 64, 678 (1980)