Trovafloxacin Mesylate

• Catalog No.: T893000
• CAS Number: 147059-75-4
• M. F.: C21H19F3N4O6S
• M. W.: 512.4589696
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 7-[(1R,5S,6R)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid; methanesulfonic acid
• IUPAC Traditional name: methanesulfonic acid; trovafloxacin
• Synonyms: Trovafloxacin methanesulfonate; Trovan; CP 99219-27; CP 99219; Trovafloxacin Monomethanesulfonate; 7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Methanesulfonate

DATABASE IDS

• CAS Number: 147059-75-4

PROPERTIES

• Apperance: White Solid
• Melting Point: >250°C (dec.)
• Solubility: DMSO
• Solubility: Methanol (Sparingly)
• Storage Condition: Refrigerator

DETAILS

Description (English)

Fluorinated quinolone antibacterial. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.

REFERENCES

• Neu, H.C., et al.: Clin. Antimicrob. Agents Chemother., 38, 2615 (1994)
• Liguori, M.J., et al.: Hepatology, 41, 177 (1994)