D-erythro-N,N,N-Trimethylsphingosine Chloride

• Catalog No.: T797150
• CAS Number: 134962-48-4
• M. F.: C21H44ClNO2
• M. W.: 378.03256
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: [(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]trimethylazanium chloride
• IUPAC Traditional name: N,N,N-trimethyl-sphingosine chloride
• Synonyms: [R-[R*,S*-(E)]]-1,3-Dihydroxy-N,N,N-trimethyl-4-octadecen-2-aminium Chloride

DATABASE IDS

• CAS Number: 134962-48-4

PROPERTIES

• Storage Condition: -20°C Freezer
• Storage Warning: Store in Freezer
• Apperance: White Solid
• Melting Point: 72-74°C
• Solubility: Methanol
• Solubility: Water

DETAILS

Description (English)

Has an inhibitory effect via blocking of transmembrane signaling on the growth of various human tumor cell lines in vitro as well as in vivo in nu/nu mice. A potent and effective cardioprotective agent that inhibits leukocyte-endothelial cell interaction

REFERENCES

• Handa, K., et al.: Biochemistry, 30, 50, 11684 (1991)
• Endo, K., et al.: Cancer Research, 51, 1613 (1991)
• Park, Y.S., et al.: Cancer Research, 54, 2213 (1991)
• Kennedy, S.D., et al.: Am. J. Clin. Pathol., 107, 1, 99 (1991)
• Campbell, B., et al: Cardivasc