2,3,4-Tri-O-trimethylsilylepilincomycin

• Catalog No.: T796865
• M. F.: C27H58N2O6SSi3
• M. W.: 623.08072

SYNONYMS

• IUPAC name: (2S,4R)-N-[(1R,2S)-2-hydroxy-1-[(2R,3S,4S,5R,6R)-6-(methylsulfanyl)-3,4,5-tris[(trimethylsilyl)oxy]oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
• IUPAC Traditional name: (2S,4R)-N-[(1R,2S)-2-hydroxy-1-[(2R,3S,4S,5R,6R)-6-(methylsulfanyl)-3,4,5-tris[(trimethylsilyl)oxy]oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
• Synonyms: Methyl 6,8-Dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-2,3,4-tris-O-(trimethylsilyl)-L-threo-α-D-galacto-octopyranoside

DETAILS

Description (English)

Protected 7-Epi lincomycin (E588550). An epimer of Lincomycin (L466200); a 6-amino, 6-deoxy-octopyraninose with strong antibiotic activity. A less potent bactericidal than its (7R)-epimer.

REFERENCES

• Le Goffic, F. et al.: J. Antimicrob. Chemother., 16, 12 (1985)
• Prior, C. et al.: J. Pharmacol. Exp. Therap., 255, 1170 (1985)