2,3,4-Tri-O-trimethylsilyllincomycin

• Catalog No.: T796860
• CAS Number: 25420-97-7
• M. F.: C27H58N2O6SSi3
• M. W.: 623.08072

SYNONYMS

• IUPAC name: (2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3S,4S,5R,6R)-6-(methylsulfanyl)-3,4,5-tris[(trimethylsilyl)oxy]oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
• IUPAC Traditional name: (2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3S,4S,5R,6R)-6-(methylsulfanyl)-3,4,5-tris[(trimethylsilyl)oxy]oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
• Synonyms: Methyl 6,8-Dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-2,3,4-tris-O-(trimethylsilyl)-D-erythro-α-D-galacto-octopyranoside

DATABASE IDS

• CAS Number: 25420-97-7

DETAILS

Description (English)

Protected Lincomycin (L466200). An antibiotic produced by Streptomyces lincolnensis. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. Inhibits bacterial protein synthesis. Antibacte

REFERENCES

• Mason, D.J., et al.: Antimicrob. Agents Chemother., 555 (1962)
• Gray, et al.: Toxicol. Appl. Pharmacol., 6, 476 (1962)
• Muti, H.Y., et al.: Anal. Profiles Drug Subs. Excip., 23, 269 (1962)