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Trilostane

Catalog No. T795600 Name Toronto Research Chemicals
CAS Number 13647-35-3 Website http://www.trc-canada.com
M. F. C20H27NO3 Telephone +1 (416) 665-9696
M. W. 329.43328 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 979

SYNONYMS

IUPAC name
(1S,2R,6R,8S,11S,12S,15S,16S)-5,15-dihydroxy-2,16-dimethyl-7-oxapentacyclo[9.7.0.02,8.06,8.012,16]octadec-4-ene-4-carbonitrile
IUPAC Traditional name
trilostane
Synonyms
Win-24540, Desopan, Modrastane, Modrenal

DATABASE IDS

CAS Number 13647-35-3

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point 247-257°C (dec.)
Solubility DMSO
Solubility Pyridine
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
An inhibitor of steroid biosynthesis. Used as an adrenocortical suppressant. Used in the treatment of breast cancer.

REFERENCES

  • Komanicky, P., et al.: J. Clin. Endocrinol. Metab., 47, 1042 (1978)
  • Mori, Y., et al., Chem. Pharm. Bull., 29, 2646 (1978)
  • Williams, C.J., et al.: Cancer Treat. Rep., 71, 1197 (1987)