(7R,8S,9S)-Trihydroxy-10S(N2-deoxyguanosyl-3'-phosphate)-7,8,9,10-tetrahydrobenzo[a]pyrene Triethylamine

• Catalog No.: T795250
• M. F.: C36H43N6O10P
• M. W.: 750.734581

SYNONYMS

• IUPAC name: triethylamine; {[(2R,3R,5R)-2-(hydroxymethyl)-5-(6-oxo-2-{[(3S,4S,5S,6R)-4,5,6-trihydroxypentacyclo[10.6.2.0^2,^7.0^9,^1^9.0^1^6,^2^0]icosa-1,7,9,11,13,15,17,19-octaen-3-yl]amino}-6,9-dihydro-1H-purin-9-yl)oxolan-3-yl]oxy}phosphonic acid
• IUPAC Traditional name: [(2R,3R,5R)-2-(hydroxymethyl)-5-(6-oxo-2-{[(3S,4S,5S,6R)-4,5,6-trihydroxypentacyclo[10.6.2.0^2,^7.0^9,^1^9.0^1^6,^2^0]icosa-1,7,9,11,13,15,17,19-octaen-3-yl]amino}-1H-purin-9-yl)oxolan-3-yl]oxyphosphonic acid; triethylamine
• Synonyms: [7R-(7α,8β,9α,10α)]-2'-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)-3'-guanylic Acid

DETAILS

Description (English)

A metabolite of the environmental carcinogen benzo(a)pyrene; a benzopyrene-DNA adduct formed during subchronic dietary exposure to carcinogen benzo(a)pyrene (BaP).

REFERENCES

• Wall, K., et al.: Carcinogenesis, 12, 783 (1991)
• Wei, Q., et al.: Cancer Res., 56, 3975 (1991)
• Baird, W., et al.: Environ. Mol. Mutagen 45, 106 (1991)