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2,6-Trifluoromethylbenzyloxy Glycine Methyl Ketone Tosylate_Molecular_structure_CAS_1144516-95-9)
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2,6-Trifluoromethylbenzyloxy Glycine Methyl Ketone Tosylate

Catalog No. T791200 Name Toronto Research Chemicals
CAS Number 1144516-95-9 Website http://www.trc-canada.com
M. F. C19H17F6NO6S Telephone +1 (416) 665-9696
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Storage Chembase ID: 179090

SYNONYMS

IUPAC name
3-azaniumyl-2-oxopropyl 2,6-bis(trifluoromethyl)benzoate 4-methylbenzene-1-sulfonate
IUPAC Traditional name
3-ammonio-2-oxopropyl 2,6-bis(trifluoromethyl)benzoate tosylate
Synonyms
TF3BOK
2,6-Bis(trifluoromethyl)benzoic Acid 3-Amino-2-oxopropyl Ester 4-Methylbenzenesulfonate

DATABASE IDS

CAS Number 1144516-95-9

PROPERTIES

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DETAILS

Description (English)
2,6-Trifluoromethylbenzyloxy Glycine Methyl Ketone is used in the synthesis electrophilic glycine analogs. Ubiquitin C-terminal electrophiles are activity-based probes for identification and mechanistic study of Ubiquitin conjugating machinery.

REFERENCES

  • Hicke, L., et al.: Nat. Rev. Mol. Cell Biol., 2, 195 (2001)
  • Borodovsky, A., et al.: Chem. Biol., 9, 1149 (2001)
  • Pickart, C., et al.: Biochim. Biophys. Acta, 1695, 55 (2001)
  • Newton, K., et al.: Cancer Invest., 25, 502 (2001)