N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride

• Catalog No.: T788530
• CAS Number: 42267-27-6
• M. F.: C9H11F3N2O4
• M. W.: 268.1898496

SYNONYMS

• IUPAC name: N-{4-[(4S)-2,5-dioxo-1,3-oxazolidin-4-yl]butyl}-2,2,2-trifluoroacetamide
• IUPAC Traditional name: N-{4-[(4S)-2,5-dioxo-1,3-oxazolidin-4-yl]butyl}-2,2,2-trifluoroacetamide
• Synonyms: N-[4-[(4S)-2,5-Dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoroacetamide; Lys(Tfa)-NCA; (S)-N-[4-(2,5-Dioxo-4-oxazolidinyl)butyl]-2,2,2-trifluoroacetamide

DATABASE IDS

• CAS Number: 42267-27-6

DETAILS

Description (English)

Used in the synthesis of new arborescent architectures of poly(L-lysine), called lysine dendrigraft (DGL) polymers. DGL polymers were prepd. through a multiple-generation scheme (up to generation 5) in a weakly acidic aq. medium by polycondensing N.vepsiln.-trifluoroacetyl-L-lysine-N-carboxyanhydride (Lys(Tfa)-NCA) onto the previous generation G(n-1) of DGL, which was used as a macroinitiator.

REFERENCES

• Svenson, S., et al.: Adv. Drug Delivery Rev., 57, 2106 (2005)
• Shen, X., et al.: Org. Biomol. Chem., 5, 3674 (2005)