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rac 1-Trichloromethyl-1,2,3,4-Tetrahydro-β-carboline

Catalog No. T774230 Name Toronto Research Chemicals
CAS Number 6649-90-7 Website http://www.trc-canada.com
M. F. C12H11Cl3N2 Telephone +1 (416) 665-9696
M. W. 289.58814 Fax +1 (416) 665-4439
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Storage Chembase ID: 178970

SYNONYMS

IUPAC name
1-(trichloromethyl)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole
IUPAC Traditional name
1-(trichloromethyl)-1H,2H,3H,4H,9H-pyrido[3,4-b]indole
Synonyms
TaClo
2,3,4,9-Tetrahydro-1-(trichloromethyl)-1H-pyrido[3,4-b]indole

DATABASE IDS

CAS Number 6649-90-7

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
1-Trichloromethyl-1,2,3,4-Tetrahydro-β-carboline (TaClo) is a dopaminergic and serotonergic neurotoxin. Liver enzymes produces TaClo via catalysis reaction of Tricloroethane with Tryptamine (T894600). TaClo destroys dopamine-producing cells and is structu

REFERENCES

  • Bringmann, G. et al.: J. Neural Transmis. Supp., 46, 245 (1995)
  • Gerlach, M. et al.: Neurosci. Lett., 257, 17 (1995)
  • Bringmann, G. et al.: J. Chrom. B Anal. Technol. Biomed. Life, 767, 321 (1995)