Trandolapril-d5 Diketopiperazine

• Catalog No.: T713517
• M. F.: C24H32N2O4
• M. W.: 412.52188

SYNONYMS

• IUPAC name: ethyl (2R)-2-[(3S,5aS,9aR,10aS)-3-methyl-1,4-dioxo-dodecahydropiperazino[1,2-a]indol-2-yl]-4-(^2H₅)phenylbutanoate
• IUPAC Traditional name: ethyl (2R)-2-[(3S,5aS,9aR,10aS)-3-methyl-1,4-dioxo-octahydro-3H-piperazino[1,2-a]indol-2-yl]-4-(^2H₅)phenylbutanoate
• Synonyms: RU 46178-d5; αS,3S,5aS,9aR,10aS)-Decahydro-3-methyl-1,4-dioxo-α-(2-phenylethyl-d5)pyrazino[1,2-a]indole-2(1H)-acetic Acid Ethyl Ester

DETAILS

Description (English)

Labelled Trandolapril Diketopiperazine (T713515). Trandolapril Diketopiperazine is a metabolite of the antihypertensive Trandolapril (Ru44570) (T713500), an angiotensin-converting enzyme inhibitor.

REFERENCES

• Bakshi, M., et al.: J. Pharm. Biomed. Anal., 28, 1011 (2002)
• Cedrowska, I., et al.: Acta Pol. Pharm., 60, 141 (2002)
• Singh, S., et al.: J. Pharm. Biomed. Anal., 41, 1037 (2002)