Tosylmethyl isocyanide

• Catalog No.: T667500
• CAS Number: 36635-61-7
• M. F.: C9H9NO2S
• M. W.: 195.23826
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 1-isocyanomethanesulfonyl-4-methylbenzene
• IUPAC Traditional name: TosMIC
• Synonyms: p-Toluenesulfonylmethylisonitrile; p-Toluenesulfonylmethyl isocyanide; 4-Toluenesulfonylmethyl Isocyanide; TosMIC; 1-[(Isocyanomethyl)sulfonyl]-4-methylbenzene; (4-Methylphenylsulfonyl)methyl Isocyanide; 4-Tolylsulfonylmethyl Isocyanide; Isocyanomethyl p-Tolyl Sulfone; NSC 631633; p-Tosylmethyl Isocyanide; p-Tosylmethyl Isonitrile; (p-Tolylsulfonyl)methyl isocyanide

DATABASE IDS

• CAS Number: 36635-61-7

PROPERTIES

• Apperance: Tan Solid
• Melting Point: 108-110°C (dec.)
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Tosylmethyl Isocyanide is used as a synthetic reagent in the preparation of variety or biologically active heterocycles such as pyrroles and imidazoles. Tosylmethyl Isocyanide is reported to inhibit [Fe]-hydrogenase with very high affinity.

REFERENCES

• Shima, S. et al.: FEBS Lett., 585, 353 (2011)
• Yamada, N. et al.: Biosci. Biotechnol. Biochem., 56, 1943 (2011)