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5'-Tosyl-2'-deoxy Guanosine_Molecular_structure_CAS_109954-64-5)
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5'-Tosyl-2'-deoxy Guanosine

Catalog No. T631700 Name Toronto Research Chemicals
CAS Number 109954-64-5 Website http://www.trc-canada.com
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SYNONYMS

IUPAC name
[(2R,3R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl 4-methylbenzene-1-sulfonate
IUPAC Traditional name
[(2R,3R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl 4-methylbenzenesulfonate
Synonyms
5'-(4-Methylbenzenesulfonate) 2'-Deoxyguanosine

DATABASE IDS

CAS Number 109954-64-5

PROPERTIES

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DETAILS

Description (English)
A novel 2'-deoxycyclonucleosides used in synthesis of α,β-methylene-2'-deoxynucleoside 5'-triphosphates as noncleavable substrates for DNA polymerases.

REFERENCES

  • Krug, F., et al.: J. Biol. Chem., 248, 1203 (1973)
  • Ahn, J., et al.: Biochem. J., 331, 79 (1973)
  • Sucato, C., et al.: Biochemistry, 46, 461 (1973)
  • Liang, F., et al.: J. Med. Chem., 51, 6460 (1973)