α-Tocopheryl Succinate

• Catalog No.: T539950
• CAS Number: 4345-03-3
• M. F.: C33H54O5
• M. W.: 530.77886

SYNONYMS

• IUPAC name: 4-oxo-4-{[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl]oxy}butanoic acid
• IUPAC Traditional name: 4-oxo-4-{[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-1-benzopyran-6-yl]oxy}butanoic acid
• Synonyms: (+)-α-Tocopheryl Succinate; Succinic Acid (+)-mono[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl] ester; Covitol 1210; Vitamin E d-α-Tocosuccinate; Butanedioic Acid 1-[(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl] Ester; (+)-2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol Hydrogen Succinate; CV 104; NSC 173849; d-α-Tocopherol Acid Succinate; d-α-Tocopheryl Acid Succinate; α-Vitamin E Succinate

DATABASE IDS

• CAS Number: 4345-03-3

DETAILS

Description (English)

A potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand). It inhibits proliferation of mesothelioma cells by selective down-regulation of fibroblast growth facto

REFERENCES

• Weber, T. et al.: Clin. Can Res., 8, 863 (2002)
• Staphelberg, M. et al.: Biochem. Biophys. Res. Comm., 318, 636 (2002)
• Ramathapuram, L.V. et al.: Cancer Immunol. Immununother., 55, 166 (2002)