Tonabersat-d6

• Catalog No.: T539502
• M. F.: C20H19ClFNO4
• M. W.: 391.8205632

SYNONYMS

• IUPAC name: N-[(3S,4S)-6-acetyl-3-hydroxy-2,2-bis(^2H₃)methyl-3,4-dihydro-2H-1-benzopyran-4-yl]-3-chloro-4-fluorobenzamide
• IUPAC Traditional name: N-[(3S,4S)-6-acetyl-3-hydroxy-2,2-bis(^2H₃)methyl-3,4-dihydro-1-benzopyran-4-yl]-3-chloro-4-fluorobenzamide
• Synonyms: N-[(3S,4S)-6-Acetyl-3,4-dihydro-3-hydroxy-2,2-(dimethyl-d6)-2H-1-benzopyran-4-yl]-3-chloro-4-fluorobenzamide; SB 220453-d6; (3S-cis)-N-(6-acetyl-3,4-dihydro-3-hydroxy-2,2-(dimethyl-d6)-2H-1-benzopyran-4-yl)-3-chloro-4-fluorobenzamide

DETAILS

Description (English)

Labelled Tonabersat (T539500). It is a cholinesterase inhibitor for treating and preventing migraine. An antimigraine agent.

REFERENCES

• Saito, R., et al.: Brain Res., 699, 109 (1995)
• Chan, W., et al.: Bioorg. Med. Chem. Lett., 9, 285 (1995)
• Nishida, M., et al.: Nature, 408, 492 (1995)
• Parsons, A., et al.: Br. J. Pharmacol., 132, 1549 (1995)