Tonabersat

• Catalog No.: T539500
• CAS Number: 175013-84-0
• M. F.: C20H19ClFNO4
• M. W.: 391.8205632

SYNONYMS

• IUPAC name: N-[(3S,4S)-6-acetyl-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl]-3-chloro-4-fluorobenzamide
• IUPAC Traditional name: N-[(3S,4S)-6-acetyl-3-hydroxy-2,2-dimethyl-3,4-dihydro-1-benzopyran-4-yl]-3-chloro-4-fluorobenzamide
• Synonyms: SB 220453; (3S-cis)-N-(6-acetyl-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)-3-chloro-4-fluorobenzamide; N-[(3S,4S)-6-Acetyl-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-3-chloro-4-fluoro-benzamide

DATABASE IDS

• CAS Number: 175013-84-0

DETAILS

Description (English)

It is a cholinesterase inhibitor for treating and preventing migraine. An antimigraine agent.

REFERENCES

• Saito, R., et al.: Brain Res., 699, 109 (1995)
• Chan, W., et al.: Bioorg. Med. Chem. Lett., 9, 285 (1995)
• Nishida, M., et al.: Nature, 408, 492 (1995)
• Parsons, A., et al.: Br. J. Pharmacol., 132, 1549 (1995)