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Tolvaptan-d7
Catalog No.	T536652	Name	Toronto Research Chemicals
CAS Number		Website	http://www.trc-canada.com
M. F.	C26H25ClN2O3	Telephone	+1 (416) 665-9696
M. W.	448.9413	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage		Chembase ID: 178728

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SYNONYMS

IUPAC name

N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-(²H₃)methyl(²H₄)benzamide

IUPAC Traditional name

N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-(²H₃)methyl(²H₄)benzamide

Synonyms

N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide-d7

OPC 41061-d7

DATABASE IDS

PROPERTIES

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DETAILS

Description (English)

Labelled Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone

REFERENCES

Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000)
Udelson, J., et al.: Circulation, 104, 2417 (2000)
Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2000)
Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2000)