(5R-cis)-Toluene-4-sulfonic Acid 5-(2,4-Difluorophenyl)-5-[1,2,4]triazol-1-ylmethyltetrahydrofuran-3-ylmethyl Ester

• Catalog No.: T535900
• CAS Number: 149809-43-8
• M. F.: C21H21F2N3O4S
• M. W.: 449.4709464
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: [(3S,5R)-5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methyl 4-methylbenzene-1-sulfonate
• IUPAC Traditional name: [(3S,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methyl 4-methylbenzenesulfonate
• Synonyms: 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol

DATABASE IDS

• CAS Number: 149809-43-8

PROPERTIES

• Apperance: White Crystalline Solid
• Melting Point: 100-102°C
• Solubility: Chloroform
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

Posaconazole intermediate. Antifungal agent.

REFERENCES

• Ator, M., et al.: J. Med. Chem., 35, 100 (1992)
• Andriole, V., et al.: J. Antimicrob. Chemother., 44, 151 (1992)
• Beuchet, P., et al.: Bioorg. Med. Chem., 9, 1599 (1992)