Tiospirone Hydrochloride

• Catalog No.: T444810
• CAS Number: 87691-92-7
• M. F.: C24H33ClN4O2S
• M. W.: 477.06242

SYNONYMS

• IUPAC name: 8-{4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione hydrochloride
• IUPAC Traditional name: 8-{4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione hydrochloride
• Synonyms: BMY 13859-1; MJ 13859-1; BMY 13859; 8-[4-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione Hydrochloride; Tiaspirone Hydrochloride

DATABASE IDS

• CAS Number: 87691-92-7

DETAILS

Description (English)

Tiospirone is an atypical antipsychotic agent. Tiospirone is used in the treatment of schizophrenia.Tiospirone acts as a 5-HT1A receptor partial agonist, 5-HT2A, 5-HT2C, and 5-HT7 receptor inverse agonist, and D2, D4, and α1-adrenergic receptor antagonist

REFERENCES

• Weiner, D.M. et al.: J. Pharmacol. Exp. Therap., 299, 268 (2001)
• Rauly-Lestienne, I. et al.: Naun.-Schmeid. Arch. Pharmacol., 376, 93 (2001)
• White, F.J. et al.: Neuropharmacology, 25, 995 (2001)