(S)-(-)-Timolol Maleate

• Catalog No.: T443710
• CAS Number: 26921-17-5
• M. F.: C17H28N4O7S
• M. W.: 432.49182
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (2Z)-but-2-enedioic acid; tert-butyl[(2S)-2-hydroxy-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propyl]amine
• IUPAC Traditional name: maleic acid; timolol
• Synonyms: (2S)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol (2Z)-2-Butenedioate Salt; (S)-(-)-3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole Hydrogen Maleate

DATABASE IDS

• CAS Number: 26921-17-5

PROPERTIES

• Apperance: White Solid
• Melting Point: 205-207°C
• Solubility: DMSO
• Storage Condition: Refrigerator

DETAILS

Description (English)

Antihypertensive; antiarrhythmic (class II); antianginal; antiglaucoma agent.

REFERENCES

• Wasson, et al.: J. Med. Chem., 15, 651 (1972)
• Franciosa, et al.: Clin. Pharmacol. Ther., 13, 138 (1972)
• Heel, R.C., et al.: Drugs, 17, 38 (1972)
• Rofman, B.A., et al.: Hypertension, 2, 643 (1972)
• Mazzo, D.J., et al.: Anal. Profiles Drug Subs., 16, 641