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(R)-(+)-Timolol Maleate_Molecular_structure_CAS_26839-77-0)
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(R)-(+)-Timolol Maleate

Catalog No. T443705 Name Toronto Research Chemicals
CAS Number 26839-77-0 Website http://www.trc-canada.com
M. F. C17H28N4O7S Telephone +1 (416) 665-9696
M. W. 432.49182 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 178657

SYNONYMS

IUPAC name
(2Z)-but-2-enedioic acid; tert-butyl[(2R)-2-hydroxy-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propyl]amine
IUPAC Traditional name
(+)-timolol; maleic acid
Synonyms
(R)-(+)-3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole Hydrogen Maleate
(2R)-1-[(1,1-Dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-2-propanol (2Z)-2-Butenedioate Salt

DATABASE IDS

CAS Number 26839-77-0

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 201-203°C
Solubility DMSO
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
Antihypertensive; antiarrhythmic (class II); antianginal; antiglaucoma agent.

REFERENCES

  • Wasson, et al.: J. Med. Chem., 15, 651 (1972)
  • Franciosa, et al.: Clin. Pharmacol. Ther., 13, 138 (1972)
  • Heel, R.C., et al.: Drugs, 17, 38 (1972)
  • Rofman, B.A., et al.: Hypertension, 2, 643 (1972)
  • Mazzo, D.J., et al.: Anal. Profiles Drug Subs., 16, 641