Tigecycline

• Catalog No.: T440015
• CAS Number: 220620-09-7
• M. F.: C29H39N5O8
• M. W.: 585.64866
• Storage: Amber Vial, -20°C Freezer

SYNONYMS

• IUPAC name: (4S,4aS,5aR,12aS)-9-[2-(tert-butylamino)acetamido]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
• IUPAC Traditional name: tigecycline
• Synonyms: Tygacil; WAY-GAR 936; Glycylcycline; (4S,4aS,5aR,12aS)-4,7-Bis(dimethylamino)-9-[[2-[(1,1-dimethylethyl)amino]acetyl]amino]-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide

DATABASE IDS

• CAS Number: 220620-09-7

PROPERTIES

• Apperance: Orange Solid
• Melting Point: 180-183°C (dec.)
• Solubility: DMSO
• Solubility: Water
• Storage Condition: Amber Vial, -20°C Freezer

DETAILS

Description (English)

A glycylcycline antibiotic, used to treat infection by drug resistant bacteria such as Staphylococcus aureus (Staph aureus) and Acinetobacter baumannii.

REFERENCES

• Lim, T., et al.: J. Antibiotics, 62, 675 (2009)
• Presterl, E., et al.: Antimicrob. Agents Chemother., 53, 3205 (2009)
• Varma, M., et al.: J. Med. Chem., 52, 4844 (2009)