Δ4-Tibolone

• Catalog No.: T437505
• CAS Number: 1162-60-3
• M. F.: C21H28O2
• M. W.: 312.44582
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1S,2R,9R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-9,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• IUPAC Traditional name: (1S,2R,9R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-9,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• Synonyms: Org-OM 38; NSC 142228; 7α-Methylnorethindrone; 17α-Ethynyl-17-hydroxy-7α-methyl-4-estren-3-one; (7α,17α)-17-Hydroxy-7-methyl-19-norpregn-4-en-20-yn-3-one

DATABASE IDS

• CAS Number: 1162-60-3

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 203-205°C
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A metabolite of Tibolone. A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.

REFERENCES

• Landgren, M., et al.: Maturitas, 50, 222 (2001)
• Wang, M., et al.: Steroids, 71, 343 (2001)
• Verheul, H., et al.: Drug Metab. Dispos., 35, 1105 (2001)
• Clarkson, T., et al.: J. Clin. Endocrinol. Metab., 86, 5396 (2001)