Thyroxine 4'-O-β-D-Glucuronide

• Catalog No.: T425630
• CAS Number: 21462-56-6
• M. F.: C21H19I4NO10
• M. W.: 952.99414

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6S)-6-(4-{4-[(2S)-2-amino-2-carboxyethyl]-2,6-diiodophenoxy}-2,6-diiodophenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6S)-6-(4-{4-[(2S)-2-amino-2-carboxyethyl]-2,6-diiodophenoxy}-2,6-diiodophenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: 4-[4-[(2S)-2-Amino-2-carboxyethyl]-2,6-diiodophenoxy]-2,6-diiodophenyl β-D-Glucopyranosiduronic Acid; Levothyroxine Phenolic Glucuronide; Thyroxine Glucuronide; (S)-4-[4-(2-Amino-2-carboxyethyl)-2,6-diiodophenoxy]-2,6-diiodophenyl β-D-Glucopyranosiduronic Acid; L-Thyroxine Glucuronide

DATABASE IDS

• CAS Number: 21462-56-6

DETAILS

Description (English)

Thyroxine 4-O-β-D-Glucuronide is a major metabolite and glucuronide conjugate of Thyroxine (T425600) formed via the glucuronidation of the phenyl hydroxyl group.

REFERENCES

• Tong, Z. et al.: Drug Metab. Dispos., 35, 2203 (2007)
• West, C.D. et al.: J. Clin. INvest., 42, 1134 (2007)