Thromboxane B2-d4

• Catalog No.: T405602
• M. F.: C20H34O6
• M. W.: 370.48036

SYNONYMS

• IUPAC name: (5Z)-7-[(2R,3S,4S)-4,6-dihydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]oxan-3-yl](3,3,4,4-^2H₄)hept-5-enoic acid
• IUPAC Traditional name: thromboxane B2-d4
• Synonyms: (5Z)-7-[(2R,3S,4S)-Tetrahydro-4,6-dihydroxy-2-[(1E,3S)-3-hydroxy-1-octenyl]-2H-pyran-3-yl]-5-heptenoic Acid-d4; 8-(1-Hydroxy-3-oxopropyl)-9,12-dihydroxy-5,10-heptadecadienoic Acid Hemiacetal-d4; (5Z,9α,13E,15S)9,11,15-Trihydroxythromboxa-5,13-dien-1-oic Acid-d4; TXB2-d4

DETAILS

Description (English)

The labelled analogue of an inactive metabolite/product of Thromboxane A2 (TBXA2): a compound involved in platelet activation and aggregation in case of a wound. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis while measurement of 1

REFERENCES

• Needleman, P. et al.: Nature, 261, 558 (1976)
• Patrono, C. et al.: J Clin. Invest., 77, 590 (1976)
• Patrono, C. et al.: Adv. Prostaglandin Thromboxane Leukot. Res., 11, 493 (1976)