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Thiostrepton

Catalog No. T375150 Name Toronto Research Chemicals
CAS Number 1393-48-2 Website http://www.trc-canada.com
M. F. C72H85N19O18S5 Telephone +1 (416) 665-9696
M. W. 1664.8868 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Hygroscopic, -20°C Freezer, Under Inert Atmosphere Chembase ID: 178584

SYNONYMS

IUPAC name
2-({2-[(1R,8S,11Z,18S,25S,26R,37R,40S,46S,53S,59S)-37-[(2S)-butan-2-yl]-18-[(2S,3R)-2,3-dihydroxybutan-2-yl]-11-ethylidene-59-hydroxy-8-[(1R)-1-hydroxyethyl]-60-[(1S)-1-hydroxyethyl]-26,40,46-trimethyl-43-methylidene-6,9,16,23,28,38,41,44,47-nonaoxo-27-oxa-3,13,20,56-tetrathia-7,10,17,24,30,36,39,42,45,48,52,58,62,63,64-pentadecaazanonacyclo[23.23.9.229,32.12,5.112,15.119,22.131,35.154,57.01,53]tetrahexaconta-2(64),4,12(63),19(62),21,29(61),30,32(60),33,51,54,57-dodecaen-51-yl]-1,3-thiazol-4-yl}formamido)-N-(1-carbamoyleth-1-en-1-yl)prop-2-enamide
IUPAC Traditional name
2-({2-[(1R,8S,11Z,18S,25S,26R,37R,40S,46S,53S,59S)-37-[(2S)-butan-2-yl]-18-[(2S,3R)-2,3-dihydroxybutan-2-yl]-11-ethylidene-59-hydroxy-8-[(1R)-1-hydroxyethyl]-60-[(1S)-1-hydroxyethyl]-26,40,46-trimethyl-43-methylidene-6,9,16,23,28,38,41,44,47-nonaoxo-27-oxa-3,13,20,56-tetrathia-7,10,17,24,30,36,39,42,45,48,52,58,62,63,64-pentadecaazanonacyclo[23.23.9.229,32.12,5.112,15.119,22.131,35.154,57.01,53]tetrahexaconta-2(64),4,12(63),19(62),21,29(61),30,32(60),33,51,54,57-dodecaen-51-yl]-1,3-thiazol-4-yl}formamido)-N-(1-carbamoyleth-1-en-1-yl)prop-2-enamide

DATABASE IDS

CAS Number 1393-48-2

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point 248-257°C (dec.)
Solubility Chloroform
Solubility Acetic Acid
MSDS Link Download
Storage Condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)
Natural antibiotic derived from Streptomyces.

REFERENCES

  • Starosta, A., et al.; Chem. Biol., 16, 1087 (2009)
  • Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2009)
  • Kwok, J., et al.: Mol. Cancer Res., 8, 24 (2009)