Theophylline-7-acetic Acid

• Catalog No.: T343860
• CAS Number: 652-37-9
• M. F.: C9H10N4O4
• M. W.: 238.2001
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 2-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-yl)acetic acid
• IUPAC Traditional name: acefylline
• Synonyms: 1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purine-7-acetic Acid; 7-Theophyllineacetic Acid; N-7-Theophyllineacetic Acid; Carboxymethyltheophylline; 7-Theophyllinylacetic Acid; 7-(Carboxymethyl)theophylline; Acefylline; Acephylline; NSC 52996; Theophyllineacetic Acid

DATABASE IDS

• CAS Number: 652-37-9

PROPERTIES

• Apperance: White Solid
• Melting Point: 268-270°C
• Solubility: DMSO
• Storage Condition: Refrigerator

DETAILS

Description (English)

A xanthine derivative with bronchodilator activity. Typically combined as salt component with other medications such as Ambroxol to treat bronchial and pulmonary diseases.

REFERENCES

• Kim, S., et al.: J. Med. Chem., 45, 2131 (2002)
• Bruno-Blanch, L., et al.: Bioorg. Med. Chem. Lett., 13, 2749 (2002)
• Foppoli, A., et al.: J. Pharm. Sci., 96, 1139(2002)