Theaflavin

• Catalog No.: T340200
• CAS Number: 4670-05-7
• M. F.: C29H24O12
• M. W.: 564.49366

SYNONYMS

• IUPAC name: 3,4,6-trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-1-benzopyran-2-yl]-5H-benzo[7]annulen-5-one
• IUPAC Traditional name: theaflavin
• Synonyms: (-)-Theaflavin; Theaflavine; 1,8-Bis[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy-5H-benzocyclohepten-5-one; Theaflavin 1; 3,4,6-Trihydroxy-1,8-bis(3α,5,7-trihydroxy-2α-chromanyl)-5H-benzocyclohepten-5-one; [2R-[2α(2R*,3R*),3α]]-1,8-Bis(3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl)-3,4,6-trihydroxy-5H-benzocyclohepten-5-one

DATABASE IDS

• CAS Number: 4670-05-7

DETAILS

Description (English)

Theaflavin is a polyphenolic compound found in black tea. Theaflavin derivatives show anti-HIV-1 activity by targeting gp41. Theaflavin is a potent inhibitor of amyloid-β (Aβ) and α-synuclein (αS) fibrillogenesis. Theaflavin also shows potent anti-tumor a

REFERENCES

• Grelle, G. et al.: Biochemistry, 50, 10624 (2011)
• Liu, S. et al.: Biochim. Biophys. Acta, 1723, 270 (2011)
• Leone, M. et al.: Cancer, Res., 63, 8118 (2011)
• Letchoumy, P.V. et al.: Arch. Med. Sci., 3, 330 (2011)