α,α,α',α'-Tetramethyl-5-methyl-1,3-benzenediacetonitrile-d12

• Catalog No.: T303617
• M. F.: C15H18N2
• M. W.: 226.31682
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 2-{3-[1-cyano-1-(^2H₃)methyl(^2H₃)ethyl]-5-methylphenyl}-2-(^2H₃)methyl(^2H₃)propanenitrile
• IUPAC Traditional name: 2-{3-[1-cyano-1-(^2H₃)methyl(^2H₃)ethyl]-5-methylphenyl}-2-(^2H₃)methyl(^2H₃)propanenitrile
• Synonyms: 2,2'-(5-Methyl-1,3-phenylene)di(2-methylpropionitrile)-d12; 3,5-Bis(2-cyano-2-methylethyl)toluene-d12; α1,α1,α3,α3,5-Pentamethyl-1,3-benzenediacetonitrile-d12; 2-[3-(Cyanodimethylmethyl)-5-methylphenyl]-2-methylpropionitrile-d12; 3,5-Bis(2-cyanoprop-2-yl)toluene-d12

PROPERTIES

• Apperance: White Solid
• Melting Point: 125-127°C
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

A labelled intermediate in the synthesis of Anastrozole, an aromatase inhibitor. Used as an antineoplastic.

REFERENCES

• Jackson, T., et al.: Org. Biomolec. Chem., 5, 3368 (2007)