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2,4,6,8-Tetrachloropyrimido[5,4-d]pyrimidine_Molecular_structure_CAS_32980-71-5)
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2,4,6,8-Tetrachloropyrimido[5,4-d]pyrimidine

Catalog No. T291365 Name Toronto Research Chemicals
CAS Number 32980-71-5 Website http://www.trc-canada.com
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SYNONYMS

IUPAC name
tetrachloropyrimido[5,4-d][1,3]diazine
IUPAC Traditional name
tetrachloropyrimido[5,4-d][1,3]diazine
Synonyms
Tetrachloropyrimido[5,4-d]pyrimidine
NSC 96654

DATABASE IDS

CAS Number 32980-71-5

PROPERTIES

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DETAILS

Description (English)
Potential tyrosine kinase signal transduction inhibitor.A pyrimido[5,4-d]pyrimidine derivative used as an intermediate in the preparation of nucleoside transporter 1 inhibitors and potential modulators of the activity of antimetabolite antitumor agents.

REFERENCES

  • Barlow, H., et al.: Bioorg. Med. Chem. Lett.,10, 585 (2000)
  • Curtin, N., et al.: J. Med. Chem., 47, 4905 (2000)
  • Saravanan, K. et al.: J. Med. Chem., 54, 1847 (2000)