2,4,6,8-Tetrachloropyrimido[5,4-d]pyrimidine

• Catalog No.: T291365
• CAS Number: 32980-71-5
• M. F.: C6Cl4N4
• M. W.: 269.903

SYNONYMS

• IUPAC name: tetrachloropyrimido[5,4-d][1,3]diazine
• IUPAC Traditional name: tetrachloropyrimido[5,4-d][1,3]diazine
• Synonyms: Tetrachloropyrimido[5,4-d]pyrimidine; NSC 96654

DATABASE IDS

• CAS Number: 32980-71-5

DETAILS

Description (English)

Potential tyrosine kinase signal transduction inhibitor.A pyrimido[5,4-d]pyrimidine derivative used as an intermediate in the preparation of nucleoside transporter 1 inhibitors and potential modulators of the activity of antimetabolite antitumor agents.

REFERENCES

• Barlow, H., et al.: Bioorg. Med. Chem. Lett.,10, 585 (2000)
• Curtin, N., et al.: J. Med. Chem., 47, 4905 (2000)
• Saravanan, K. et al.: J. Med. Chem., 54, 1847 (2000)