Tetrabenazine

• Catalog No.: T284000
• CAS Number: 58-46-8
• M. F.: C19H27NO3
• M. W.: 317.42258
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-one
• IUPAC Traditional name: tetrabenazine
• Synonyms: Ro 1-9569; (3R,11bR)-rel-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one; NSC 172187; NSC 169886; cis-2-Oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine; (+/-)-Tetrabenazine; Rubigen

DATABASE IDS

• CAS Number: 58-46-8

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 128-130°C
• Solubility: Chloroform
• Solubility: DMSO
• Storage Condition: Refrigerator

DETAILS

Description (English)

Dopamine depleting agent. An antidyskinetic; antipsychotic.

REFERENCES

• Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966)
• Janovic, J., et al.: Ann. Neurol., 11, 41 (1966)
• Janovic, J., et al.: Neurology, 38, 391 (1966)