Δ1-Testolactone

• Catalog No.: T154800
• CAS Number: 968-93-4
• M. F.: C19H24O3
• M. W.: 300.39206

SYNONYMS

• IUPAC name: (1R,2S,7S,10S,11R)-7,11-dimethyl-6-oxatetracyclo[8.8.0.0^2,^7.0^1^1,^1^6]octadeca-12,15-diene-5,14-dione
• IUPAC Traditional name: testolactone
• Synonyms: 17a-Oxa-D-homo-1,4-androstadiene-3,17-dione; 1,2-Dehydrotestololactone; Δ1-Dehydrotestololactone; Δ1-Testololactone; Fludestrin; (4aS,4bR,10aR,10bS,12aS)-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-10a,12a-dimethyl-2H-phenanthro[2,1-b]pyran-2,8(4bH)-dione; Δ1-Testolactone; D-Homo-17a-oxaandrosta-1,4-diene-3,17-dione; 1,2-Didehydrotestololactone; NSC 23759; SQ 9538; Teolit; Teslac; Teslak; Testolacton; 13-Hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic Acid δ-Lactone; 1-Dehydrotestololactone

DATABASE IDS

• CAS Number: 968-93-4

PROPERTIES

• Apperance: White Solid
• Melting Point: 221-223°C
• Solubility: Chloroform

DETAILS

Description (English)

Antineoplastic; non-selective steroidal aromatase inhibitor that prevents the conversion from androgen to estrogen. Used in in the treatment of familial male precocious puberty. An effective anti-tumor agent.

REFERENCES

• Dunkel, L.: Mol. Cell. Endocrinol., 254, 207 (2006)
• Eugster, E. A.: Treat. Endocrinol., 3, 141 (2006)
• Holbeck, S.L. et al.: Mol. Cancer Therap., 9, 1451 (2006)