Tepoxalin

• Catalog No.: T103250
• CAS Number: 103475-41-8
• M. F.: C20H20ClN3O3
• M. W.: 385.8441
• Storage: Hygroscopic, Refrigerator, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-3-yl]-N-hydroxy-N-methylpropanamide
• IUPAC Traditional name: tepoxalin
• Synonyms: RWJ 20485; ORF 20485; 5-(4-Chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-1H-pyrazole-3-propanamide

DATABASE IDS

• CAS Number: 103475-41-8

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 123-125°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, Refrigerator, Under Inert Atmosphere

DETAILS

Description (English)

Non-steroidal anti-inflammatory drug (NSAID) with potent anti-inflammatory and analgesic properties approved for veterinary use. It has inhibitory effect on cyclooxygenase and 5-lipxygenase activity as well as inhibiting the production of cytokines in per

REFERENCES

• Argentieri, D.C. et al.: J. Pharmacol. Exp. Therap., 271, 1399 (1994)
• Agnello, K.A. et al.: Am. J. Vet. Res., 66, 966 (1994)
• Fiebich, B.L. et al.: Neuropharmacol., 38, 1325 (1994)