Tn Epitope

• Catalog No.: T020050
• CAS Number: 67262-86-6
• M. F.: C11H20N2O8
• M. W.: 308.2851
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (2S)-2-amino-3-{[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propanoic acid
• IUPAC Traditional name: GalNAcα1-Ser
• Synonyms: N-Acetyl-α-D-galactosaminyl-1-O-serine; O-[2-(Acetylamino)-2-deoxy-α-D-galactopyranosyl]-L-serine; Serinyl 2-Acetamido-2-deoxy-α-galactopyranoside

DATABASE IDS

• CAS Number: 67262-86-6

PROPERTIES

• Apperance: Off-White to Yellow Solid
• Melting Point: 182-188°C (dec.)
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Storage Warning: HYGROSCOPIC

DETAILS

Description (English)

A cancer associated carbohydrate tumor antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. Has been used or considered for use in human vaccines.

REFERENCES

• Springer, G., et al.: Science, 224, 1198 (1984)
• Springer, G., et al.: J. Mol. Med., 75, 594 (1984)
• Iida, S., et al.: J. Biol. Chem., 274, 10697 (1984)
• Wu, A., et al.: Biochem. J., 371, 311 (1984)