T Epitope, Serinyl

• Catalog No.: T020000
• CAS Number: 60280-57-1
• M. F.: C17H30N2O13
• M. W.: 470.4257

SYNONYMS

• IUPAC name: (2S)-2-amino-3-{[(2S,3R,4R,5R,6R)-3-acetamido-5-hydroxy-6-(hydroxymethyl)-4-{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}propanoic acid
• IUPAC Traditional name: (2S)-2-amino-3-{[(2S,3R,4R,5R,6R)-3-acetamido-5-hydroxy-6-(hydroxymethyl)-4-{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}propanoic acid
• Synonyms: 3-(O-b-D-galactosyl)-N-acetyl-α-D-galactosaminyl-1-O-serine; Serinyl 2-Acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-α-D-galactopyranoside; O-[2-(Acetylamino)-2-deoxy-3-O-β-D-galactopyranosyl-α-D-galactopyranosyl]-L-serine

DATABASE IDS

• CAS Number: 60280-57-1

DETAILS

Description (English)

A cancer associated carbohydrate tumor antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. Has been used or considered for use in human vaccines.

REFERENCES

• Kim, J.M., and Roy, R.: Tetrahedron Lett., 38, 3487 (1997)
• Qiu, D., and Koganty, R.: Tetrahedron Lett., 38, 961 (1997)
• Toyokuni, T., and Singhal, A.K.: Chem. Soc. Rev., 231, (1995)