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Tenofovir Monomethyl Ester

Catalog No. T018495 Name Toronto Research Chemicals
CAS Number 123155-85-1 Website http://www.trc-canada.com
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SYNONYMS

IUPAC name
({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(methoxy)phosphinic acid
IUPAC Traditional name
{[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxy}methyl(methoxy)phosphinic acid
Synonyms
(±)-[[2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-phosphonic Acid Monomethyl Ester

DATABASE IDS

CAS Number 123155-85-1

PROPERTIES

Certificate of Analysis Download
Apperance Light Yellow Solid
Solubility Methanol
Solubility Water
MSDS Link Download

DETAILS

Description (English)
Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.

REFERENCES

  • Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997)
  • Wyles, D., et al.: Clin Infect. Dis., 40, 174 (1997)
  • Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (1997)
  • Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (1997)