Teniposide

• Catalog No.: T018400
• CAS Number: 29767-20-2
• M. F.: C32H32O13S
• M. W.: 656.65368
• Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere

SYNONYMS

• IUPAC name: (10R,11R)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-(thiophen-2-yl)-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^3,^7.0^1^1,^1^5]hexadeca-1(9),2,7-trien-12-one
• IUPAC Traditional name: (10R,11R)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-(thiophen-2-yl)-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^3,^7.0^1^1,^1^5]hexadeca-1(9),2,7-trien-12-one
• Synonyms: Tenoposide; NSC 122819; EPT; Vumon; (5R,5aR,8aR,9S)-5,8,8a,9-Tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-O-[(R)-2-thienylmethylene]-β-D-glucopyranosyl]oxy]furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one; S 122819; VM 26; Vehem; Vehem-Sandoz

DATABASE IDS

• CAS Number: 29767-20-2

PROPERTIES

• Apperance: White Solid
• Melting Point: 213-215°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under inert atmosphere

DETAILS

Description (English)

A semi-synthetic derivative of Podophyllotoxin. Antineoplastic.

REFERENCES

• Stahlen, H., Eur. J. Cancer, 6, 303 (1970)
• Hacker, M., et al.: Cancer Res., 37, 3287 (1970)
• Clark, P.I., et al.: Clin. Pharmacokinet., 12, 223 (1970)