Temsirolimus-13C3,d7

• Catalog No.: T017963
• M. F.: C56H87NO16
• M. W.: 1033.26504451

SYNONYMS

• IUPAC name: (1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30R,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.0^4,^9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexyl 3-hydroxy-2-[hydroxy(^1^3C,^2H₂)methyl]-2-(^1^3C,^2H₃)methyl(3-^1^3C,^2H₂)propanoate
• IUPAC Traditional name: (1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30R,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.0^4,^9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexyl 3-hydroxy-2-[hydroxy(^1^3C,^2H₂)methyl]-2-(^1^3C,^2H₃)methyl(3-^1^3C,^2H₂)propanoate
• Synonyms: Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate-13C3,d7; CCL-779-13C3,d7

DETAILS

Description (English)

Labelled ester analog of Rapamycin.

REFERENCES

• Raymond, E., et al.: J. Clin. Oncol., 22, 2336 (2004)
• Galanis, E., et al.: J. Clin. Oncol., 23, 5294 (2005)