Temsirolimus-d3

• Catalog No.: T017962
• M. F.: C56H87NO16
• M. W.: 1030.28708
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30R,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.0^4,^9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexyl 3-hydroxy-2-(hydroxymethyl)-2-(^2H₃)methylpropanoate
• IUPAC Traditional name: (1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30R,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.0^4,^9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexyl 3-hydroxy-2-(hydroxymethyl)-2-(^2H₃)methylpropanoate
• Synonyms: Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-(methyl-d3)-propanoate; CCL-779-d3

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 114-116°C
• Solubility: Chloroform
• Solubility: Ethyl Acetate
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Labelled ester analog of Rapamycin.

REFERENCES

• Raymond, E., et al.: J. Clin. Oncol., 22, 2336 (2004)
• Galanis, E., et al.: J. Clin. Oncol., 23, 5294 (2005)