Tauroursodeoxycholic Acid Sodium Salt (90%)

• Catalog No.: T009200
• CAS Number: 35807-85-3
• M. F.: C26H44NNaO6S
• M. W.: 521.68543
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: sodium 2-[(4R)-4-[(1S,2S,5R,7S,9S,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]ethane-1-sulfonate
• IUPAC Traditional name: sodium 2-[(4R)-4-[(1S,2S,5R,7S,9S,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]ethanesulfonate
• Synonyms: 2-[[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic Acid Sodium Salt; Sodium Tauroursodeoxycholate; 3α,7β-Dihydroxy-5β-cholan-24-oic Acid N-(2-Sulfoethyl)amide; Ursodeoxycholyltaurine

DATABASE IDS

• CAS Number: 35807-85-3

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 173-175°C
• Solubility: DMSO
• Solubility: Methanol
• Solubility: Water
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways.

REFERENCES

• Alvarez, E., et al.: J. Biol. Chem., 266, 15277 (1991)
• Alvaro, D., et al.: J. Clin. Invest., 96, 665 (1991)
• Alpini, G., et al.: Hepatology, 34, 868 (1991)
• Higuchi, H., et al.: J. Biol. Chem., 278, 454 (2003)