Taurolithocholic Acid Sodium Salt

• Catalog No.: T009100
• CAS Number: 6042-32-6
• M. F.: C26H44NNaO5S
• M. W.: 505.68603
• Storage: Refrigerator

SYNONYMS

• IUPAC name: sodium 2-[(4R)-4-[(2S,5R,7R,10R,11S,15R)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]ethane-1-sulfonate
• IUPAC Traditional name: sodium 2-[(4R)-4-[(2S,5R,7R,10R,11S,15R)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]ethanesulfonate
• Synonyms: Sodium Taurolithocholate; 2-[[(3α,5β)-3-Hydroxy-24-oxocholan-24-yl]amino]ethanesulfonic Acid Sodium Salt; N-(3α-Hydroxy-5β-cholan-24-oyl)taurine Monosodium Salt; NSC 681057

DATABASE IDS

• CAS Number: 6042-32-6

PROPERTIES

• Apperance: White Solid
• Melting Point: 199-201°C
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

The major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but not to M2 or M3 receptors.

REFERENCES

• Javitt, N.B., et al.: J. Clin. Invest., 47, 1002 (1968)
• Bowmer, C., et al.: J. Pharm. Pharmacol., 37, 812 (1968)
• Ha, C., et al.: J. Biomed. Sci., 7, 114 (1968)
• Zaton, A., et al.: Chem. Biol. Interact., 124, 1 (1968)