Taurodeoxychloic Acid Sodium Salt

• Catalog No.: T009005
• CAS Number: 1180-95-6
• M. F.: C26H44NNaO6S
• M. W.: 521.68543
• Storage: Refrigerator

SYNONYMS

• IUPAC name: sodium 2-[(4R)-4-[(1S,2S,5R,7R,10R,11S,14R,15R,16S)-5,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]ethane-1-sulfonate
• IUPAC Traditional name: sodium taurodeoxycholate
• Synonyms: Sodium Taurodesoxycholate; Sodium Deoxytaurocholate; Sodium taurodeoxycholate; Taurodeoxycholate Sodium; Taurodeoxycholic Acid Sodium Salt; Sodium 3α,12α-Dihydroxy-5β-cholanoyltaurate; N-(3α,12α-Dihydroxy-5β-cholan-24-oyl)-taurine Monosodium Salt

DATABASE IDS

• CAS Number: 1180-95-6

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 200-203°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.

REFERENCES

• Cheng, K., et al.: Biochem. J., 330, 353 (1998)
• Cheng, K., et al.: Cancer Res., 63, 6744 (1998)
• Bellacosa, A., et al.: Adv. Cancer Res., 94, 29 (1998)
• Cheng, K., et al.: Biochem. Pharmacol., 70, 1035 (1998)
• Fang, D., et al.: J. Biol. Chem., 282, 11221