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Taurodeoxychloic Acid Also See T009005_Molecular_structure_CAS_516-50-7)
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Taurodeoxychloic Acid Also See T009005

Catalog No. T009000 Name Toronto Research Chemicals
CAS Number 516-50-7 Website http://www.trc-canada.com
M. F. C26H45NO6S Telephone +1 (416) 665-9696
M. W. 499.7036 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Chembase ID: 129714

SYNONYMS

IUPAC name
2-[(4R)-4-[(1S,2S,5R,7R,10R,11S,14R,15R,16S)-5,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-14-yl]pentanamido]ethane-1-sulfonic acid
IUPAC Traditional name
taurodeoxycholate
Synonyms
Taurodesoxycholic Acid
N-(3α,12α-Dihydroxy-5β-cholan-24-oyl)taurine
2-[[(3α,5β,12β)-3,12-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic Acid
Deoxycholyltaurine
Deoxytaurocholic acid
Tudcabil

DATABASE IDS

CAS Number 516-50-7

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.

REFERENCES

  • Cheng, K., et al.: Biochem. J., 330, 353 (1998)
  • Cheng, K., et al.: Cancer Res., 63, 6744 (1998)
  • Bellacosa, A., et al.: Adv. Cancer Res., 94, 29 (1998)
  • Cheng, K., et al.: Biochem. Pharmacol., 70, 1035 (1998)
  • Fang, D., et al.: J. Biol. Chem., 282, 11221