Taurochenodeoxycholic Acid-d5 (Major)

• Catalog No.: T008132
• M. F.: C26H45NO6S
• M. W.: 499.7036

SYNONYMS

• IUPAC name: 2-[(4R)-4-[(1S,2S,5R,7R,9R,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]ethane-1-sulfonic acid
• IUPAC Traditional name: 2-[(4R)-4-[(1S,2S,5R,7R,9R,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]ethanesulfonic acid
• Synonyms: 12-Deoxycholyltaurine-d5; N-(3α,7α-dihydroxy-5β-cholan-24-oyl)taurine-d5; Chenodeoxycholyltaurine-d5; 12-Desoxycholyltaurine-d5; 2-[[(3α,5β,7α)-3,7-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic Acid-d5; 3α,7α-Dihydroxy-N-(2-sulfoethyl)-5β-cholan-24-amide-d5; Chenyltaurine-d5; Taurochenodesoxycholic acid

DETAILS

Description (English)

Labelled analogue of Taurochenodeoxycholic Acid, a bile acid conjugate and metabolite Taurolithocholic Acid (T009100) with antiinflammatory activity. Taurochenodeoxycholic Acid has been shown to inhibit hepatocyte apoptosis through suppression of Bid tran

REFERENCES

• Emerman, S. et al.: J. Biol. Chem., 242, 661 (1967)
• Takikawa, Y. et al.: Falk Symp., 120, 249 (1967)
• Li, P. et al.: Zhong. Shour. Xue., 28, 1317 (1967)