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Taurochenodeoxycholic Acid Sodium Salt

Catalog No. T008130 Name Toronto Research Chemicals
CAS Number 516-35-8 Website http://www.trc-canada.com
M. F. C26H45NO6S Telephone +1 (416) 665-9696
M. W. 499.7036 Fax +1 (416) 665-4439
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Storage Chembase ID: 129712

SYNONYMS

IUPAC name
2-[(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-14-yl]pentanamido]ethane-1-sulfonic acid
IUPAC Traditional name
taurochenodeoxycholate
Synonyms
Taurochenodesoxycholic Acid Sodium Salt
3α,7α-Dihydroxy-N-(2-sulfoethyl)-5β-cholan-24-amide
Chenyltaurine Sodium Salt
Chenodeoxycholyltaurine Sodium Salt
12-Desoxycholyltaurine Sodium Salt
2-[[(3α,5β,7α)-3,7-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic Acid Sodium Salt
N-(3α,7α-dihydroxy-5β-cholan-24-oyl)taurine Sodium Salt
12-Deoxycholyltaurine Sodium Salt

DATABASE IDS

CAS Number 516-35-8

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
Taurochenodeoxycholic Acid is a bile acid conjugate and metabolite Taurolithocholic Acid (T009100) with antiinflammatory activity. Taurochenodeoxycholic Acid has been shown to inhibit hepatocyte apoptosis through suppression of Bid translocation to mitoch

REFERENCES

  • Emerman, S. et al.: J. Biol. Chem., 242, 661 (1967)
  • Takikawa, Y. et al.: Falk Symp., 120, 249 (1967)
  • Li, P. et al.: Zhong. Shour. Xue., 28, 1317 (1967)