Taspine

• Catalog No.: T007800
• CAS Number: 602-07-3
• M. F.: C20H19NO6
• M. W.: 369.36796
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 5-[2-(dimethylamino)ethyl]-7,14-dimethoxy-2,9-dioxatetracyclo[6.6.2.0^4,^1^6.0^1^1,^1^5]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione
• IUPAC Traditional name: 5-[2-(dimethylamino)ethyl]-7,14-dimethoxy-2,9-dioxatetracyclo[6.6.2.0^4,^1^6.0^1^1,^1^5]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione
• Synonyms: 1-[2-(Dimethylamino)ethyl]-3,8-dimethoxy-[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione; NSC 688259; Taspin; Thaspine

DATABASE IDS

• CAS Number: 602-07-3

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: >300°C (dec.)
• Solubility: Chloroform
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

It is an alkaloid isolated from Radix et Rhizoma Leonticis. It shows various pharmaceutical properties: bacteriostatic, wound healing, cytotoxicity, immunosuppression, acetilcholinesterase inhibition, and inhibition of the activity of tumor angiogenesis.

REFERENCES

• Perdue, G.P., et al.: J. Pharm. Sci., 68, 124 (1979)
• Tsacheva, I., et al.: J. Biosci., 59, 528 (1979)
• Zhang, Y., et al.: Cancer Lett., 262 103 (1979)